Bio Spec Overview
Ignite Creation Date:
2025-12-25 @ 2:23 AM
Last Modification Date:
2025-12-25 @ 2:23 AM
Retention:
SAMPLES_WITH_DNA
Description:
Hematocrit and peripheral blood parasitemia in thin and thick films will be assessed at T=0 (enrolment) then 6-hourly until parasite clearance (two consecutive negative thick smears per 500 white blood cells). Plasma creatinine will be measured 24-hourly for 72 hours, at discharge and day 14. Venous blood gas and lactate will be assessed 6-hourly until lactate \<2 mmol/L.
Arterial blood gas will be collected at T0 and after 24 hours if the subject is in respiratory distress, defined as respiratory rate \> 30 breaths per minute and SpO2 \<92% on room air. More frequent hematological and biochemical measurements may be done if clinically indicated at the discretion of the treating clinician. Plasma cell-free hemoglobin (CFH) will be analyzed at hour 0, 6, 24, 48, 72 and day 7 in the severe malaria group and only hour 0 in sepsis and uncomplicated malaria groups. Blood cultures and additional microbiology assays will be drawn at enrolment and performed locally.
Arterial blood gas will be collected at T0 and after 24 hours if the subject is in respiratory distress, defined as respiratory rate \> 30 breaths per minute and SpO2 \<92% on room air. More frequent hematological and biochemical measurements may be done if clinically indicated at the discretion of the treating clinician. Plasma cell-free hemoglobin (CFH) will be analyzed at hour 0, 6, 24, 48, 72 and day 7 in the severe malaria group and only hour 0 in sepsis and uncomplicated malaria groups. Blood cultures and additional microbiology assays will be drawn at enrolment and performed locally.
Section:
Hematocrit and peripheral blood parasitemia in thin and thick films will be assessed at T=0 (enrolment) then 6-hourly until parasite clearance (two consecutive negative thick smears per 500 white blood cells). Plasma creatinine will be measured 24-hourly for 72 hours, at discharge and day 14. Venous blood gas and lactate will be assessed 6-hourly until lactate \<2 mmol/L.
Arterial blood gas will be collected at T0 and after 24 hours if the subject is in respiratory distress, defined as respiratory rate \> 30 breaths per minute and SpO2 \<92% on room air. More frequent hematological and biochemical measurements may be done if clinically indicated at the discretion of the treating clinician. Plasma cell-free hemoglobin (CFH) will be analyzed at hour 0, 6, 24, 48, 72 and day 7 in the severe malaria group and only hour 0 in sepsis and uncomplicated malaria groups. Blood cultures and additional microbiology assays will be drawn at enrolment and performed locally.