Description Module

Description Module

The Description Module contains narrative descriptions of the clinical trial, including a brief summary and detailed description. These descriptions provide important information about the study's purpose, methodology, and key details in language accessible to both researchers and the general public.

Description Module path is as follows:

Study -> Protocol Section -> Description Module

Description Module


Ignite Creation Date: 2025-12-25 @ 4:16 AM
Ignite Modification Date: 2025-12-25 @ 4:16 AM
NCT ID: NCT04092920
Brief Summary: Commercially available implant surfaces are moderately roughened surfaces and they are obtained by acid-etching following alumina or titanium oxide grit-blasting. Although the micro-rough implants can be successful in compromised clinical scenarios, the bioinert nature of titanium surfaces cannot stimulate a more rapid bone regeneration and mechanical fixation of dental implants. Laser surface treatment is used to produce an implant surface modification on the nano-scale with controlled and reproducible patterns in addition to exhibiting a sterilizing effect and achieving efficient oxidation .
Detailed Description: For dental implant to be successful, a direct contact between the bone tissue and the surface of the implant should be developed \& this physiological phenomenon is known by the term of osseointegration. Initially, it was supposed that to achieve osseointegration, implants had to be submerged under the mucosa \& left without any loading for a period of 3-4 months in mandible and 6-8 months in maxilla. Recently immediate implant placement at the time of extraction has become a viable treatment alternative, this approach provides the advantages of decreasing the patient's discomfort, the treatment's duration and costs. Aiming to reduce healing process to limit such changes in the soft \& hard tissues and reducing treatment time, several alterations in both surgical and restorative procedures has been introduced. From an implant design perspective, two approaches including the fields of biomaterials and/or biomechanics have been most utilized; implant body design which aim to increase the primary stability and surface modifications to allow faster osseointegration process. Rough implant surface is modified by different techniques. Among these different techniques, interest in of using laser to achieve roughened surfaces. Commercially available implant surfaces are moderately roughened surfaces and they are obtained by acid-etching following alumina or titanium oxide grit-blasting. Although the micro-rough implants can be successful in compromised clinical scenarios, the bioinert nature of titanium surfaces cannot stimulate a more rapid bone regeneration and mechanical fixation of dental implants.
Study: NCT04092920
Study Brief:
Protocol Section: NCT04092920