Description Module
The Description Module contains narrative descriptions of the clinical trial, including a brief summary and detailed description. These descriptions provide important information about the study's purpose, methodology, and key details in language accessible to both researchers and the general public.
Description Module path is as follows:
Study -> Protocol Section -> Description Module
Description Module
Ignite Creation Date:
2025-12-24 @ 5:24 PM
Ignite Modification Date:
2025-12-24 @ 5:24 PM
NCT ID:
NCT04930250
Brief Summary:
Whilst a cause-and-effect relationship between consumption of oat ß-glucans and reduction in PPGR has been demonstrated, little is understood about its:
* Application to liquid matrices: There are few studies which looked into the effect of a dose of ß-glucan applicable to beverages. Previous studies have explored oat ß-glucan doses between 2g to 13g per serving of test product (Note: the oat ß-glucan dose for the proposed trial is \<2g).
* Impact following processing: Collectively, oat processing, ß-glucan structure and its physiological impact on PPGR are closely linked. Some studies have investigated the effect of oat processing or dosage on PPGR, but to our knowledge, no study has systematically characterised the effect of processing on oat structure, and clinically measured its subsequent impact on PPGR.
Detailed Description:
The proposed study is a randomised, double blind, controlled, crossover trial to investigate the postprandial effects on glycemic response and related biomarkers/biological surrogates in five test product beverages:
This study will investigate the post-prandial effects of five test products, including two controls:
1. Beverage powder with 12% oat bran processed with method A (Test Product: TP-1)
2. Beverage powder with 12% oat bran processed with method B (Test Product: TP-2)
3. Beverage powder with 12% oat bran processed with method C (Test Product: TP-3)
4. Beverage powder with 12% minimally-processed oat bran (Positive Control) (Test Product: TP-PC)
5. Beverage powder without oat bran (Negative Control) (Test Product: TP-NC)
Study:
NCT04930250
Study Brief:
Protocol Section:
NCT04930250