Description Module
The Description Module contains narrative descriptions of the clinical trial, including a brief summary and detailed description. These descriptions provide important information about the study's purpose, methodology, and key details in language accessible to both researchers and the general public.
Description Module path is as follows:
Study -> Protocol Section -> Description Module
Description Module
Ignite Creation Date:
2025-12-24 @ 6:35 PM
Ignite Modification Date:
2025-12-24 @ 6:35 PM
NCT ID:
NCT06749457
Brief Summary:
The purpose of this study is to evaluate the safety and pharmacokinetics (PK) of AZD7760 when given as an intravenous infusion to healthy participants (Phase I) or participants with end-stage kidney disease receiving hemodialysis through a central venous catheter (Phase IIa).
Detailed Description:
In the Phase I portion of the study, participants will be randomized to receive one of 3 dosages of AZD7760 or placebo as a single intravenous infusion.
Study details include:
* A 28-day Screening Period.
* A Dosing Period of 3 days in which a single intravenous infusion will be given on Day 1.
* A Follow-up Period of 12 months from the time of administration of the study intervention.
In the Phase IIa portion of the study, participants will be randomized to receive either AZD7760 or placebo as 2 intravenous infusions given 3 months apart.
Study details include:
* A 28-day Screening Period.
* A Dosing Period in which 2 intravenous infusions will be given 3 months apart (Day 1 and Day 91).
* A Follow-up Period of 12 months after the last administration of the study intervention on Day 91.
Study:
NCT06749457
Study Brief:
Protocol Section:
NCT06749457