Description Module
The Description Module contains narrative descriptions of the clinical trial, including a brief summary and detailed description. These descriptions provide important information about the study's purpose, methodology, and key details in language accessible to both researchers and the general public.
Description Module path is as follows:
Study -> Protocol Section -> Description Module
Description Module
Ignite Creation Date:
2025-12-24 @ 12:56 PM
Ignite Modification Date:
2025-12-24 @ 12:56 PM
NCT ID:
NCT01622361
Brief Summary:
The purpose of this study is to compare neo-adjuvant therapy of cytotoxic chemotherapy versus GnRHa with tamoxifen , of response rate(RR) in patients of hormone responsive and HER2 negative, lymph node positive, primary breast cancer in premenopausal women.
Detailed Description:
1. Primary objective
: Response Rate-MRI and/or Caliper
2. Secondary objectives
* Pathologic complete response
* Rate of conservation surgery
* Ki-67 changes and its relationship to treatment response
* Length of time to maximum response within the treatment period
* Tolerability of two treatments
* Disease-free survival(DFS)
* Overall survival
Study:
NCT01622361
Study Brief:
Protocol Section:
NCT01622361