Description Module

Description Module

The Description Module contains narrative descriptions of the clinical trial, including a brief summary and detailed description. These descriptions provide important information about the study's purpose, methodology, and key details in language accessible to both researchers and the general public.

Description Module path is as follows:

Study -> Protocol Section -> Description Module

Description Module


Ignite Creation Date: 2025-12-24 @ 10:08 PM
Ignite Modification Date: 2025-12-24 @ 10:08 PM
NCT ID: NCT07207135
Brief Summary: This study investigated the effects of isometric exercises applied to the quadriceps and hamstring muscles at different knee joint angles on balance, joint position sense, and functional performance in healthy individuals. Thirty participants aged 20-30 years were randomized into four groups and performed an eight-week training program, three times per week. Outcome measures included the Y Balance Test, digital goniometer assessments for joint position sense, and functional performance tests (stair climb and 30-second sit-to-stand). The results aim to identify which knee joint angles are most effective for improving neuromuscular function and may guide future rehabilitation and training protocols.
Detailed Description: Isometric exercises applied to the quadriceps and hamstring muscles are widely used both in rehabilitation programs and in improving physical fitness in athletes. Isometric contractions occur when the muscle generates tension without changing its length, making them especially suitable in conditions where joint movement is limited or contraindicated. Previous studies have demonstrated the benefits of isometric training in increasing muscle strength, enhancing proprioception, and supporting functional performance. However, there is no clear consensus regarding the effects of isometric exercises performed at different knee joint angles on balance, joint position sense, and functional capacity. The aim of this study was to investigate the effects of isometric exercises applied to the quadriceps and hamstring muscles at different knee angles (15°-90°, 30°-105°, 45°-120°, 60°-135°) on balance, joint position sense, and functional performance in healthy individuals. Participants aged 20-30 years, without knee pain, previous knee surgery, or pathologies preventing ambulation, were included. All participants were randomized into four groups. Each group performed progressive resistance exercises for the hip and ankle, combined with isometric exercises of the quadriceps and hamstring muscles at the specified knee angles. The training program lasted eight weeks, with sessions three times per week. During each session, isometric contractions were performed against resistance for 10 seconds at the assigned knee angles, with standardized rest periods between sets. The number of repetitions was progressively increased throughout the program. Assessments were conducted at baseline and after eight weeks. The following outcome measures were used: Balance: Y Balance Test Joint position sense: Digital goniometer measurements Functional performance: Stair climb test and 30-second sit-to-stand test The hypothesis of the study was that isometric exercises performed at different knee joint angles would result in different responses in balance, joint position sense, and functional performance. The findings are expected to provide valuable insights both for improving physical fitness in healthy populations and for guiding rehabilitation protocols in clinical populations.
Study: NCT07207135
Study Brief:
Protocol Section: NCT07207135