Description Module
The Description Module contains narrative descriptions of the clinical trial, including a brief summary and detailed description. These descriptions provide important information about the study's purpose, methodology, and key details in language accessible to both researchers and the general public.
Description Module path is as follows:
Study -> Protocol Section -> Description Module
Description Module
Ignite Creation Date:
2025-12-25 @ 12:36 AM
Ignite Modification Date:
2025-12-25 @ 12:36 AM
NCT ID:
NCT07253467
Brief Summary:
This study examines how different standing postures and whole-body vibration conditions affect spinal reflex activity. Participants will stand in various positions-with and without vibration of two amplitudes-and H-reflex responses from the soleus muscle will be recorded. Additionally, vibration-induced reflex latency will be assessed across multiple vibration frequencies.
Detailed Description:
Participants will engage in a structured set of experimental tasks designed to evaluate the effects of postural mechanical loading, and whole-body vibration.
The protocol includes four primary standing conditions:
Quiet bipedal stance,
Single-leg stance on the left side,
Bipedal stance during whole-body vibration (WBV), and
Single-leg stance on the left side during WBV.
During all WBV conditions, two vibration amplitudes-2.2 mm and 1.2 mm-will be applied sequentially to assess amplitude-dependent modulation of reflex responses.
Throughout each condition, H-reflex recordings from the soleus muscle will be collected to quantify changes in spinal reflex excitability under varying postural and vibratory loads. In addition to these measurements, vibration-induced reflex latency will be evaluated by delivering vibratory stimuli at multiple frequencies (30, 32, 34, and 36 Hz) within the same experimental protocol. This approach allows for a comprehensive analysis of how both posture and vibratory parameters influence neuromuscular reflex pathways.
The investigators conducted an a priori power analysis for a repeated-measures ANOVA (within-subjects design) to determine the required sample size. The analysis was based on a medium expected effect size, specified as partial eta squared (ηₚ²) = 0.06, which corresponds to an effect size of f = 0.25. The investigators set the alpha error probability at 0.05 and the desired statistical power (1-β) at 0.80. The design included one group with five repeated measurements, assuming a correlation of 0.70 among repeated measures. Under these conditions, the critical F value was 2.5652405, with 4 numerator degrees of freedom and 48 denominator degrees of freedom. The power analysis indicated that a total sample size of 13 participants is required. The required sample size was calculated using G\*Power version 3.1.9.4 (Franz Faul, University of Kiel, Germany).
Study:
NCT07253467
Study Brief:
Protocol Section:
NCT07253467