Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:26 AM
Ignite Modification Date:
2025-12-25 @ 1:26 AM
NCT ID:
NCT02022293
Eligibility Criteria:
Inclusion Criteria:
* Patients must have received radiation therapy for histologically confirmed nasopharyngeal carcinoma.
* Prior irradiation \<3 years prior to study entry.
* Male or fertile women who are willing to take contraception during the trial.
* Age 40-65 years old.
* Carotid stenosis \< 50%.
* LDL-C between 100mg/dL（2.5mmol/L）and 190mg/dL（4.9mmol/L）.
* Ability to understand and the willingness to sign a written informed consent document.
Exclusion Criteria:
* History of bleeding related to tumor or radiotherapy during or after radiation.
* Evidence of tumor invasion to major vessels(for example the carotid artery).
* Severe complications, such as history of stroke, myocardial infarction, liver diseases, thyroid dysfunction, inadequately controlled hypertension and epilepsy.
* Familial hypercholesterolemia.
* Taking lipid-lowing drugs.
* Aspartate aminotransferase(AST) or alanine aminotransferase(ALT) \>upper limits of normal (ULN), creatinine \>ULN.
* Allergic history of atorvastatin.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
40 Years
Maximum Age:
65 Years
Study:
NCT02022293
Study Brief:
Protocol Section:
NCT02022293