Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:27 AM
Ignite Modification Date:
2025-12-25 @ 1:27 AM
NCT ID:
NCT02735694
Eligibility Criteria:
Inclusion Criteria:
* Moderate to severe obstructive or central sleep apnea (Apnea Hypopnea Index \> 30/hr).
* Minimum Oxygen saturation during respiratory events \>70% throughout sleep during the clinical sleep study.
Exclusion Criteria:
* Contraindication to the use of cycloserine, namely history of allergy to cycloserine, seizures, depression, severe anxiety or psychosis, excessive use of alcohol or renal failure.
* Past or current history of tuberculosis
* Hypercapnia \> 55 millimeters of mercury during the diagnostic clinical sleep study.
* Neuromuscular disease.
* Obesity-hypoventilation syndrome.
* Pregnancy.
* Significant co-morbidities: Dialysis-dependant renal failure, severe asthma or chronic lung disease, congestive heart failure, previous stroke.
* Recent (within 3 months) myocardial infarction or Active coronary ischemia event.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
21 Years
Maximum Age:
70 Years
Study:
NCT02735694
Study Brief:
Protocol Section:
NCT02735694