Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:10 AM
Ignite Modification Date:
2025-12-25 @ 2:10 AM
NCT ID:
NCT03368560
Eligibility Criteria:
Inclusion Criteria:
* 60-80 years of age
* major depressive disorder, as per the results of an interview by a trained rater using the Structured Clinical Interview for DSM-5 and subsequently confirmed by the psychiatrist
* Mild to moderate depression as confirmed by a score on the HAM-D 17 between 8 and 23
* Have failed at least two trials of antidepressants, given at adequate doses for adequate duration during the current episode
* Able to follow verbal instructions and sit without physical discomfort for 45 minutes
* Willing and able to attend at least 75% of all Sudarshan Kriya Yoga (SKY) sessions
* Willing to dedicate 25-30 minutes/day to SKY practice at home
* Low risk of suicide based on a clinical initial interview and during follow-up interviews at weeks 4, 8 and 12.
Exclusion Criteria:
* Uncontrolled hypertension, seizure disorder, psychosis, substance abuse, or dementia
* Currently participating in other similar studies or currently practicing any type of formal meditation, mindfulness or breathing techniques
* A major surgery within 6 weeks prior to commencement of or scheduled during, the study intervention
* A traumatic brain injury
* Any contraindications to MRI will also be excluded
* Healthy control participants must have no significant mental health issues, or contraindications to MRI.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
60 Years
Maximum Age:
80 Years
Study:
NCT03368560
Study Brief:
Protocol Section:
NCT03368560