Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:16 AM
Ignite Modification Date:
2025-12-25 @ 2:16 AM
NCT ID:
NCT00642460
Eligibility Criteria:
Inclusion Criteria:
* Patients aged 2-17 years of age
* Systemic juvenile idiopathic arthritis with \>= 6 months persistent activity
* Presence of active disease (\>=5 active joints, or \>=2 active joints + fever + steroids)
* Inadequate clinical response to nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids due to toxicity or lack of efficacy
Exclusion Criteria:
* Wheelchair-bound or bed-ridden
* Any other autoimmune, rheumatic disease or overlap syndrome other than systemic juvenile idiopathic arthritis
* Intravenous long-acting corticosteroids or intra-articular corticosteroids within 4 weeks of baseline, or throughout study
* Disease-modifying antirheumatic drugs (DMARDs), other than methotrexate
* Previous treatment with tocilizumab
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
2 Years
Maximum Age:
17 Years
Study:
NCT00642460
Study Brief:
Protocol Section:
NCT00642460