Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 2:38 AM
Ignite Modification Date:
2025-12-25 @ 2:38 AM
NCT ID:
NCT02021734
Eligibility Criteria:
Inclusion Criteria:
* All included individuals must provide informed consent
* All genetic disorders are included
* All ethnic backgrounds are accepted
* Disease must be genetic with no evident environmental cause
* Evidence of Mendelian Transmission determined by fulfilling one of the following criteria:
* Multiple affected family members (at least first degree relative with disease)
* History of consanguinity
* Severe disease in newborn in the absence of family history
* Sydromic disease in single individuals
* Congenital abnormality affecting major organ system(s)
* Mendelianized extremes of common disease (eg sever familial diabetes/ obesity/ hypertension)
Exclusion Criteria:
* Individuals who do no consent to be included
* Mendelian disease for which a gene mutation has already been identified
* Individuals for which a molecular diagnosis has already been established by alternative method
* Disease for which an environmental factor is most likely the cause
* Disease for which late age of onset rule out Mendelian transmission
* Common diseases for which late age of onset rule out Mendelian transmission
Healthy Volunteers:
True
Sex:
ALL
Study:
NCT02021734
Study Brief:
Protocol Section:
NCT02021734