Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 3:04 AM
Ignite Modification Date:
2025-12-25 @ 3:04 AM
NCT ID:
NCT05888233
Eligibility Criteria:
Inclusion Criteria:
In order to be eligible to participate in this study, an individual must meet all of the following criteria:
1. Veteran
2. African American
3. Resistant hypertension diagnosis (defined as blood pressure greater than 140/90 mmHg at 2 clinic visits despite the use of 3 antihypertensive medications at pharmacologically effective doses)
4. Locale - Birmingham, AL and surrounding areas
Exclusion Criteria:
1. History of heart failure
2. Chronic kidney disease (estimated creatinine clearance \< 60 ml/min)
3. Chronic steroid therapy
4. Known coronary artery disease
5. Known causes of secondary hypertension
6. Already taking Allopurinol
Magnetic Resonance Imaging Exclusion
1. Claustrophobia
2. Cardiac implantable electronic device (permanent pacemaker and/or intracardiac defibrillator)
3. Metal clips and/devices or other item that specifically prohibit safe CMR
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
75 Years
Study:
NCT05888233
Study Brief:
Protocol Section:
NCT05888233