Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 5:09 AM
Ignite Modification Date:
2025-12-25 @ 5:09 AM
NCT ID:
NCT00773227
Eligibility Criteria:
Inclusion Criteria:
* Man or woman \<18-75\> years old
* Oculopharyngeal muscular dystrophy confirmed by genetic diagnosis (mutation of the GCG) on the chromosome 14)
* Oculopharyngeal muscular dystrophy with UES dysfunction
1. salivary or alimentary stasis at fibroscopy of swallowing above the UES,
2. decreased opening of the UES at videofluoroscopy of swallowing A decreased of the pharyngeal propulsion may be associated Written consent of the patient
Exclusion Criteria:
* History of myotomy of the UES in the context of the Oculopharyngeal muscular
* Dystrophy;
* HIV, hepatitis B or C tuberculosis);
* Lupus, rheumatoid polyarthritis, sarcoïdosis, collagenosis) ;
* Other neuromuscular diseases ;
* History of malignant tumor ;
* History of neck radiotherapy ;
* Renal failure (creatinine clearance \<60ml/min)
* Liver failure ;
* Pregnancy ;
* Follow up less than 24 months:
* Patients who refuse to sign the consent;
* No social security.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
75 Years
Study:
NCT00773227
Study Brief:
Protocol Section:
NCT00773227