Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 2:55 PM
Ignite Modification Date:
2025-12-24 @ 2:55 PM
NCT ID:
NCT00512759
Eligibility Criteria:
Inclusion Criteria:
* Acute HF expressed by acute dyspnea New York Heart Association (NYHA) class III or IV, and a BNP-level ≥ 500 pg/ml. The diagnosis of acute HF is additionally based on typical symptoms and clinical findings, supported by appropriate investigations such as ECG, chest X-ray, and Doppler-echocardiography as recommended by current ESC guidelines on the diagnosis and treatment of acute HF
Exclusion Criteria:
* Cardiopulmonary resuscitation \< 7 days
* Cardiogenic shock, ST-elevation myocardial infarction, or other clinical conditions that require immediate ICU admission or urgent PTCA
* Systolic blood pressure lower than 100 mmHg at presentation
* Primary rhythmogenic cause of acute decompensation (ventricular tachycardia, reentry tachycardia, atrial fibrillation or atrial flutter with a ventricular rate exceeding 140 beats per minute)
* NSTEMI as primary diagnosis
* Severe aortic stenosis
* Adult congenital heart disease as primary cause of acute HF
* Hypertrophic obstructive cardiomyopathy
* Chronic kidney disease with creatinin levels \> 250 µmol/l
* Bilateral renal artery stenosis
* Severe sepsis or other causes of high output failure
* Cirrhosis of the liver CHILD class C
* Previous adverse reactions to nitrates
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00512759
Study Brief:
Protocol Section:
NCT00512759