Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 3:25 PM
Ignite Modification Date:
2025-12-24 @ 3:25 PM
NCT ID:
NCT00639392
Eligibility Criteria:
Inclusion Criteria:
* 18 years and older
* Male or female with sickle cell disease
* Pain related to sickle cell disease Patient history of health services utilization for acute SCD-related pain Patient history of use of narcotic analgesics for pain control within the past 6 months
* Able to tolerate hydration with 500 mL D51/2 NS prior to Zoledronic Acid or placebo
Exclusion Criteria:
* Calculated creatinine clearance less than 60 mL/min
* Current active dental problems
* Recent (within 6 weeks) or planned dental or jaw surgery (e.g., extraction,implants)
* History of cirrhosis or chronic symptomatic liver disease; acute liver disease
* History of aspirin-induced asthma
* History of allergy to zoledronic acid or similar chemical-entities
* Pregnant or nursing
* No prior bisphosphonate use
* Receipt of an investigational drug within 30 days
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
70 Years
Study:
NCT00639392
Study Brief:
Protocol Section:
NCT00639392