Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2026-03-26 @ 3:21 PM
Ignite Modification Date:
2026-03-26 @ 3:21 PM
NCT ID:
NCT05999227
Eligibility Criteria:
Inclusion Criteria:
* Histologically confirmed T3-4N0M0 or T1-4N+M0 (according to the 8th edition of the International Union Against Cancer TNM staging system) rectal adenocarcinoma and treatment naïve;
* No severe hematologic, cardiac, pulmonary, hepatic, or renal functional abnormalities or immunodeficiency diseases;
* An Eastern Cooperative Oncology Group Performance Status of 0-1;
* Patients who agree to undergo 68Ga-FAPI-04 and 18F-FDG PET imaging.
Exclusion Criteria:
* Any experiences of anti-programmed death ligand 1 (PD-L1) or anti-PD-1 antibody treatment;
* A history of pelvic radiation;
* The presence of autoimmune disease;
* Hypersensitive to any monoclonal antibodies;
* History of interstitial lung disease;
* Active and uncontrolled infection.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT05999227
Study Brief:
Protocol Section:
NCT05999227