Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 4:00 PM
Ignite Modification Date:
2025-12-24 @ 4:00 PM
NCT ID:
NCT02952066
Eligibility Criteria:
Inclusion Criteria:
* Competent to understand informed consent
* Diagnosis of moderate to severe persistent allergic asthma.
* Clinical need for diagnostic bronchoscopy for assessment of asthmatic symptoms (e.g., to assess presence of chronic infection with non-tuberculous mycobacteria or other infectious agents as a cause for lack of asthma control) or therapeutic bronchoscopy for management of asthmatic symptoms (e.g., thermoplasty).
* Asthmatic subjects with history of positive skin test to confirm presence of allergy.
* Asthmatic subjects with pre-albuterol forced expiratory volume in the first second (FEV1) of \<70% of the predicted value.
* Non-asthmatic patients will include those patients with solitary pulmonary nodules and healthy individuals with acute lung atelectasis (e.g. airway blocked by mucus plugs or foreign object).
* Scheduled for a diagnostic or therapeutic bronchoscopy procedure.
Exclusion Criteria:
* Inability to perform pulmonary function testing
* Unstable asthma control for asthmatic subjects
* An asthma exacerbation within the past month
* History of intubation for asthma
* History of smoking
* History of prematurity
* History of any lung disease or disorder except asthma
* History of congenital or acquired heart disease
* Pregnant/lactating females
* Any serious concurrent systemic disease including but not limited to diabetes, coronary artery disease, vasculitis, etc.
* History of heart arrhythmias including supraventricular tachycardia
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
60 Years
Study:
NCT02952066
Study Brief:
Protocol Section:
NCT02952066