Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 4:16 PM
Ignite Modification Date:
2025-12-24 @ 4:16 PM
NCT ID:
NCT00818766
Eligibility Criteria:
Inclusion Criteria:
* Adults aged 18 years or older undergoing elective thoracic surgery at Brigham \& Women's Hospital. The majority of these patients will be undergoing lung resection for either the evaluation of a lung mass, or for the removal of a known malignancy. Some participants may be undergoing biopsy or removal of a mediastinal mass.
* Undergoing thoracic surgery procedure expected to require tube thoracostomy.
* Ability to give informed consent
Exclusion Criteria:
* Patients undergoing the following complex thoracic surgical procedures:
* Pneumonectomy
* Decortication
* Chemical pleurodesis
* Pleurectomy
* Lung volume reduction
* Esophagectomy
* Patients with the following conditions:
* Prior diagnosis of empyema or lung abscess.
* Cystic fibrosis
* Known or suspected pneumonia pre-operatively.
* Known hypersensitivity to beta-lactam antibiotics and vancomycin
* Current or recent antibiotic use within one week of surgery.
* Anticipated requirement for postoperative antibiotic in addition to 48 hours of cefazolin or vancomycin.
* Renal insufficiency with estimated creatinine clearance \<60 ml/minute.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00818766
Study Brief:
Protocol Section:
NCT00818766