Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 12:20 PM
Ignite Modification Date:
2025-12-24 @ 12:20 PM
NCT ID:
NCT06639061
Eligibility Criteria:
Inclusion Criteria:
* Aged of 20-65 years.
* Meet a diagnosis of PTSD according to DSM-5 as tested by a structured clinical interview (Clinician-Administered PTSD Scale for DSM-5 - CAPS-5).
* CAPS-5 total score greater or equal to 33.
* Endorsement of intrusive symptoms (flashbacks, nightmares, or intrusive memories) with a frequency of at least 3 times a week.
* Meeting the accepted criteria for inclusion in an MRI examination.
Exclusion Criteria:
* Meeting a diagnosis of Complex PTSD or personality disorder.
* Psychotic disorder, bipolar disorder, or a developmental neuropsychological disorder (autism, mental retardation).
* Use of psychiatric medications (except for the medications listed in section 4.a of the study protocol if the medication dosage is stable in the last three months and does not change during the study.
* Exclusion rules in TMS research (see guidelines).
* Use of the following drugs: imipramine, amitriptyline, doxepin, nortriptyline, maprotiline, chlorpromazine, clozapine, foscarnet, ganciclovir, ritonavir, amphetamines, cocaine, (MDMA, ecstasy), phencyclidine (PCP, angel's dust), ketamine, gamma- hydroxybutyrate (GHB), alcohol, theophylline
* Epilepsy or use of anti-epileptic drugs.
* Traumatic head injuries or head surgery.
* Implanted metallic body (except fillings/amalgam bites/orthodontic fixations approved for MRI), electrodes or a pacemaker.
* Migraines
* Pregnant women
* Hearing problems
* Drinking alcohol 24 hours before the TMS session
* Repeated episodes of fainting with loss of consciousness and/or an event of fainting with loss of consciousness in the past year.
* The accepted exclusion criteria for an MRI examination
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
20 Years
Maximum Age:
65 Years
Study:
NCT06639061
Study Brief:
Protocol Section:
NCT06639061