Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 4:25 PM
Ignite Modification Date:
2025-12-24 @ 4:25 PM
NCT ID:
NCT06837766
Eligibility Criteria:
Inclusion Criteria:
* diagnosis of acute hepatic decompensation on chronic liver disease with grade ACLF ≥ 2 (diagnosable in the presence of at least two defined organ failures according to the CLIF-C-OF score);
* hemoabsorbent treatment with Cytosorb;
* patients aged ≥ 18 years at the time of diagnosis;
* Informed Consent.
Exclusion Criteria
* patients aged \< 18 years;
* fulminant liver failure;
* chronic end-stage liver failure with chronic encephalopathy and/or chronic refractory ascites;
* acute on chronic hepatic decompensation with grade 0 or 1 ACLF;
* clinical signs or history of congestive heart failure (NYHA class 3-4 before the acute phase of the disease or documented EF \< 35% or PCWP \> 18 mmHg) or acute coronary syndrome
* state of immunosuppression (rheumatological and immunological diseases, HIV, immunosuppressive therapy);
* previous organ transplant.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT06837766
Study Brief:
Protocol Section:
NCT06837766