Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 4:55 PM
Ignite Modification Date:
2025-12-24 @ 4:55 PM
NCT ID:
NCT04341350
Eligibility Criteria:
Inclusion Criteria:
* Patient aged 18 and over
* Patient requiring mechanical ventilation for at least 24 hours
* The patient requires continuous and immediate sedation for more comfort, safety and to facilitate the administration of survival measures.
* Consent obtained from patient or relative
Exclusion Criteria:
Patient hospitalized for the following reasons for admission:
* Cardiac arrest
* State of refractory epilepticus
* Head trauma
* Stroke
* Hearing, visual or aphasia disorders before inclusion making it impossible to take the CAM-ICU
* Sedation started more than 24 hours ago
* Impairment of cognitive functions and / or dementia
* Contraindication to halogenated gases (personal or family history of malignant hyperthermia, acute or chronic neuromuscular disease, hepatocellular insufficiency with PT \<30%)
* Severe acute respiratory distress syndrome (ARDS) (Berlin criteria: PaO2 / FiO2 \<100 after ventilatory optimisation))
* PaCO2 at inclusion\> 50 mmHg after ventilatory optimisation
* Patient for whom a procedure of "limitation of active therapies" is envisaged at inclusion
* Patient under guardianship or curatorship
* Minor patient
* Pregnant or breastfeeding woman
* Patient not affiliated to the social security scheme
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04341350
Study Brief:
Protocol Section:
NCT04341350