Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:01 PM
Ignite Modification Date:
2025-12-24 @ 5:01 PM
NCT ID:
NCT04212650
Eligibility Criteria:
Inclusion Criteria:
* Underwent primary hip arthroscopy
* Underwent baseline quantitative MRI at The Steadman Clinic (TSC)
* Single, localized, grade 3 or 4 cartilage lesion of the acetabulum or femoral head treated with Bone Marrow Stimulation (BMS; i.e. microfracture)
* Aged 18-60 at time of surgery
* Tonnis grade 1 or less
Exclusion Criteria:
* Two or more cartilage lesions of grade 3 or 4
* Less than 2 mm of minimal hip joint space
* Osteoarthritis or diffuse change of cartilage
* Non-English speaking
* Prior hip surgery on operative hip
* Pre-existing bony deformity caused by previous fracture(s)
* Synovial chondromatosis
* Pigmented Villonodular Synovitis (PVNS)
* Dysplasia (center edge angle \<20 degrees)
* History of Avascular Necrosis (AVN), Perthes disease, or slipped capital femoral epiphysis (SCFE)
* Inflammatory arthritis or other arthritis caused by autoimmune disease
* Patients allergic to any active or inactive ingredient of losartan
* Patients taking medication with known losartan interaction, including phenobarbital, rifampin, and fluconazole.
* Subjects that are currently taking losartan
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
60 Years
Study:
NCT04212650
Study Brief:
Protocol Section:
NCT04212650