Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:09 PM
Ignite Modification Date:
2025-12-24 @ 5:09 PM
NCT ID:
NCT07106450
Eligibility Criteria:
Inclusion Criteria:
* Age 30-55 years
* Sedentary lifestyle (exercise \<1 day/week for at least 3 months prior to enrollment)
* Able to provide informed consent
* For Control Group: BMI \< 27 kg/m², normal glucose tolerance, no more than 1 feature of metabolic syndrome
* For Prediabetic Group: BMI \> 30 kg/m², at least 3 features of metabolic syndrome including prediabetes (defined as fasting plasma glucose 100-125 mg/dL OR 2-hour post-load glucose on 75g OGTT 140-199 mg/dL OR HbA1C 5.7-6.4%)
Exclusion Criteria:
* Pregnancy (confirmed by pregnancy test in women of childbearing potential)
* Type 2 diabetes mellitus
* Cardiovascular contraindications to resistance exercise
* Medical conditions that would interfere with muscle or adipose tissue biopsy procedures
* Use of medications that significantly affect glucose metabolism or exercise response
* Active participation in structured exercise programs (\>1 day/week) within 3 months of enrollment
* Inability to safely participate in resistance exercise protocol
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
30 Years
Maximum Age:
55 Years
Study:
NCT07106450
Study Brief:
Protocol Section:
NCT07106450