Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:24 PM
Ignite Modification Date:
2025-12-24 @ 5:24 PM
NCT ID:
NCT04522050
Eligibility Criteria:
Inclusion Criteria:
* Patients with newly histologically confirmed non-keratinizing carcinoma (according to WHO histological type)
* Tumor staged as Ⅲ-Ⅳa (according to the 8th AJCC edition staging system)
* Age :18-60
* Performance status: KPS \> 70
* Normal liver function test: Alanine Aminotransferase (ALT), Aspartate Aminotransferase (AST) \< 1.5×upper limit of normal (ULN) concomitant with alkaline phosphatase (ALP) \< 2.5×ULN, and bilirubin \< ULN
* Renal: creatinine clearance \> 60ml/min
* Adequate marrow: leucocyte count \> 4×109/L, neutrophil count \> 2×109/L, and platelet count \> 100×109/L
* Written informed consent
Exclusion Criteria:
* History of allergy to related drugs
* Prior malignancy (except adequately treated carcinoma in-situ of the cervix or basal/squamous cell carcinoma of the skin)
* History of previous RT (except for non-melanomatous skin cancers outside intended RT treatment volume)
* Prior chemotherapy or surgery (except diagnostic) to primary tumor or nodes
* Any severe intercurrent disease, which may bring unacceptable risk or affect the compliance of the trial, for example, unstable cardiac disease requiring treatment, renal disease, chronic hepatitis, diabetes with poor control (fasting plasma glucose \> 1.5×ULN), and emotional disturbance
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
60 Years
Study:
NCT04522050
Study Brief:
Protocol Section:
NCT04522050