Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:36 PM
Ignite Modification Date:
2025-12-24 @ 5:36 PM
NCT ID:
NCT03043768
Eligibility Criteria:
INCLUSION CRITERIA
\- Male and female PD patients (idiopathic parkinsonism, Hoehn and Yahr \[H\&Y\] scores 1-2) aged 35 to 80 years and age-and gender matched healthy control subjects
EXCLUSION CRITERIA
* any dermatological disorders affecting the cutaneous testing regions
* treatment with tricyclic antidepressants, noradrenergic antidepressants, beta-blockers, alpha-adrenergic agonists or antagonists, cholinergic or anti-cholinergic agents
* known allergy to phenylephrine or acetylcholine
* elevated alcohol consumption (more than 4 alcoholic beverages/week)
* nicotine consumption within the past 5 years
* known disorders affecting autonomic functions (including diabetes, pure autonomic failure, inflammatory demyelinating polyradiculoneuropathies, multiple system atrophy, atypical Parkinson syndromes, body mass index over 25 kg/m2, acute or chronic renal disease, gout, rheumatoid arthritis, Lupus, Sjogren 's syndrome, Triple- A syndrome, autonomic neuropathies not related to PD)
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
35 Years
Maximum Age:
80 Years
Study:
NCT03043768
Study Brief:
Protocol Section:
NCT03043768