Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:42 PM
Ignite Modification Date:
2025-12-24 @ 5:42 PM
NCT ID:
NCT03929068
Eligibility Criteria:
Inclusion Criteria:
* Diagnosis of ALS or PLS
* Age greater than 18 years
* Clinically significant spasticity.
Exclusion Criteria:
* Individuals currently taking carbidopa-levodopa or with known hypersensitivity of any component of carbidopa-levodopa
* Narrow-angle glaucoma
* Current use of a non-selective monoamine oxidase inhibitor (MAOI)
* History of malignant melanoma or suspicious skin lesions
* History of depression, suicidal ideation, or psychosis
* History of myocardial infarction, ventricular arrhythmia, or severe cardiopulmonary disease
* Uncontrolled hypertension
* Asthma
* Renal disease
* Hepatic disease
* Endocrine disease
* History of peptic ulcer
* Pregnant and/or breastfeeding
* Current participation in another interventional study
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT03929068
Study Brief:
Protocol Section:
NCT03929068