Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:44 PM
Ignite Modification Date:
2025-12-24 @ 5:44 PM
NCT ID:
NCT03142568
Eligibility Criteria:
Inclusion Criteria:
* Receiving positive airway pressure (nasal continuous airway pressure, nasal intermittent positive pressure ventilation, or nasal cannula flow \> 1LPM) or mechanical ventilation (high frequency or conventional)
* \<29 weeks gestational age at birth
* 7-28 (inclusive) days postnatal age at time of randomization
Exclusion Criteria:
* Currently receiving vasopressors
* Currently receiving inhaled nitric oxide
* Baseline mean arterial pressure \< gestational age (in weeks) plus postnatal age (in weeks) within 2 hours of sildenafil administration
* Known allergy to sildenafil
* Known sickle cell disease
* AST \> 225 U/L \< 72 hours prior to randomization
* ALT \> 150 U/L \< 72 hours prior to randomization
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
7 Days
Maximum Age:
28 Days
Study:
NCT03142568
Study Brief:
Protocol Section:
NCT03142568