Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:56 PM
Ignite Modification Date:
2025-12-24 @ 5:56 PM
NCT ID:
NCT00679068
Eligibility Criteria:
Inclusion Criteria:
* Adult patients with World Health Organization (WHO) functional class II-III.
* A systemic pulse oximetry (SpO2) between 70% and 90% at rest with room air and a baseline 6-minute walk distance between 150 and 450 m were required for inclusion.
* PAH confirmed by cardiac catheterization as mean pulmonary arterial pressure greater or equal to25 mm Hg, pulmonary capillary wedge pressure lower 15 mm Hg,
Exclusion Criteria:
* Patients were excluded if they had patent ductus arteriosus (for hemodynamic assessment difficulties)
* complex congenital heart defect
* left ventricular dysfunction (left ventricular ejection fraction lower 40%)
* restrictive lung disease (total lung capacity lower 70% predicted)
* obstructive lung disease (forced expiratory volume in 1 second \[FEV1\] lower 70% predicted
* with FEV1/forced vital capacity lower 60%)
* or previously diagnosed coronary artery disease.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
80 Years
Study:
NCT00679068
Study Brief:
Protocol Section:
NCT00679068