Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 6:31 PM
Ignite Modification Date:
2025-12-24 @ 6:31 PM
NCT ID:
NCT03768557
Eligibility Criteria:
Inclusion Criteria:
* Participants are willing and able to give informed consent for participation in the study
* Male or female, aged between 18 and 55
* Body mass index (BMI) within the range of 19 - 30 kg/m2
* Sufficiently fluent in English to understand the tasks and instructions
* Female subjects must be outside of their pre-menstrual week on the testing day
Exclusion Criteria:
* Current or past history of any psychiatric disorder (e.g. depression, anxiety)
* Any medical contra-indication (for example hepatic impairment)
* Current use of any medication which, in the opinion of the study physician, will interfere with minocycline or cause any contraindications
* Known hypersensitivity to tetracyclines or to any of the excipients in minocycline capsules
* Steroidal or non-steroidal anti-inflammatory medication within preceding 2 weeks, including aspirin and ibuprofen
* Congenital or acquired immune deficiency (including participants receiving immunosuppressive or antimitotic drugs)
* Current pregnancy or breastfeeding
* Current substance misuse
* Recent (\< 3 months) use of psychotropic drugs
* Participant in a psychological or medical study involving the use of medication within the last 3 months
* Participant in another study using the same / a similar battery of cognitive / emotional tasks in the last 3 months
* Current smoker of more than 5 cigarettes per day
* Dyslexia (given the nature of the computer tasks)
* Lactose intolerance (placebo is composed of lactose capsules)
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
55 Years
Study:
NCT03768557
Study Brief:
Protocol Section:
NCT03768557