Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 6:31 PM
Ignite Modification Date:
2025-12-24 @ 6:31 PM
NCT ID:
NCT07114757
Eligibility Criteria:
Inclusion Criteria:
\- We will enroll patients (at least 18 years of age and younger than 85 years old) with subacute stroke (thus occurring 7-45 days before screening), admitted to hospital, with persistently high systolic PB (≥140 mm Hg computed as the mean of 3 repeated measurements taken within 5 minutes between 8.00am and 8.30 am on 2 consecutive days, thus totaling 6 measurements), or a non-dipper profile at ambulatory BP monitoring, despite therapy with ≥2 anti-hypertensive drugs at maximum tolerated dose. Patients should be medically stable with no severe complications such as infections, or worsening of neurological status that would require immediate and intensive medical or surgical intervention.
Exclusion Criteria:
* ⦁ Patients with cerebral bleeding due to arteriovenous malformation or intracranial aneurysm
* Hemodynamic instability
* Comorbidity with life expectancy ≤ 1 year
* Renal artery anatomy, which prevents the procedure
* Reno vascular disease
* Vascular occlusion, which prevents the procedure
* Secondary hypertension
* Subject has known hypersensitivity or contraindication to any of the study drugs
* The subject is currently participating in another investigational drug or device clinical study
* Pregnancy or nursing
* Presence of other anatomic or comorbid conditions or other medical, social, or psychological conditions that, in the investigator's opinion, could limit the subject's ability to participate in the clinical investigation or to comply with follow-up requirements or impact the scientific soundness of the clinical investigation results
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
84 Years
Study:
NCT07114757
Study Brief:
Protocol Section:
NCT07114757