Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 6:33 PM
Ignite Modification Date:
2025-12-24 @ 6:33 PM
NCT ID:
NCT02493257
Eligibility Criteria:
Inclusion criteria:
* Non-allergic irritant rhinitis (NAIR) patients as defined by history (symptoms of nasal congestion, rhinorrhea, nasal itching or sneezing upon exposure to nasal irritants)
* Patients with positive optical rhinometer (ORM) response with intranasal challenge with 0.5 millimolar (mM) capsaicin as described by Lambert et al 2012
* Confirmed negative skin prick test to common allergens (which rules out allergic rhinitis)
Exclusion Criteria:
* History of sinonasal surgery
* Chronic rhinosinusitis
* Inflammatory or granulomatous diseases
* Asthma
* Allergic rhinitis
* Immunocompromised state
* Radiation to the head and neck
* Intranasal steroid use \>4 wks
* Intranasal or systemic antihistamine x 3 days
* Intranasal or systemic decongestants x 3 days
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
70 Years
Study:
NCT02493257
Study Brief:
Protocol Section:
NCT02493257