Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 6:40 PM
Ignite Modification Date:
2025-12-24 @ 6:40 PM
NCT ID:
NCT04373057
Eligibility Criteria:
Inclusion Criteria:
* Plan to undergo allogeneic HCT for any cancer or non-cancer illness
* Age 18-80 years
* Karnofsky Performance Status \>70
Exclusion Criteria:
* Pregnant/lactating
* Malabsorption syndrome, short bowel or chologenic diarrhea
* At time of enrollment, Grade 2 or higher GI symptoms per NCI-CTCAE
* Active treatment with other prebiotics, probiotics, or herbal supplementation (ok if stops before enrollment)
* Active treatment with antibiotics (with the exception of prophylactic antibiotics)
* Concurrent enrollment on the Duke HCT Home Transplant study or another clinical trial targeting GVHD; patients who are enrolled in observational or non-pharmacologic intervention trials (for example, the Duke HCT Research-POP Pre and Peri-HCT Optimization Program aka "R-POP") or pharmacologic or cellular therapy trials with other targets (for example, NK DLI) are NOT excluded
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
80 Years
Study:
NCT04373057
Study Brief:
Protocol Section:
NCT04373057