Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 7:24 PM
Ignite Modification Date:
2025-12-24 @ 7:24 PM
NCT ID:
NCT04247503
Eligibility Criteria:
Inclusion Criteria:
1. An individual who has previously consented to the Biospecimen Resource for Pancreas Research (Substudy #2 Family Studies) - IRB 355-06
2. Individual who does not have a personal history of pancreatic cancer and meets one of the following:
1. Has relatives in family that contains pancreatic cancer, and carries a known germline mutation in APC, ATM, BRCA1, BRCA2, CDKN2A, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, STK11, or TP53.
OR
2. Is a first- or second-degree blood relative of an individual with a diagnosis of pancreatic ductal adenocarcinoma (PDAC) and this PDAC patient has a germline mutation in APC, ATM, BRCA1, BRCA2, CDKN2A, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, STK11, or TP53.
OR
3. Is a first- or second-degree blood relative of an individual with a germline mutation in one of these genes and where the mutation carrier is also a first-degree relative to a PDAC case.
OR
4. Is a blood relative to a PDAC patient in a family that contains three blood relatives (all maternal side or all paternal side) with PDAC.
3. Age
1. 50 or older, OR
2. Or within 10 years of the age of diagnosis of the youngest PDAC blood relative.
4. Individual with a valid United States mailing address. -
Exclusion Criteria:
1. Individual who has a personal history of PDAC
2. Individual who has received a bone marrow transplant, who has had a blood transfusion within the last 7 days, or who has an active hematologic malignancy (i.e., leukemia or lymphoma).
3. Individual who is unable to sign the informed consent because of mental incompetency or psychiatric illness
4. Individual who is non-English speaking
5. Individual who is a prison inmate -
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04247503
Study Brief:
Protocol Section:
NCT04247503