Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 12:58 PM
Ignite Modification Date:
2025-12-24 @ 12:58 PM
NCT ID:
NCT00487461
Eligibility Criteria:
Inclusion Criteria:
* 18-85 years old inclusive
* Subarachnoid hemorrhage diagnosed by CT on admission
* Randomizable within 732 hours of subarachnoid hemorrhage
* Saccular intracranial aneurysm proven by cerebral angiography or computed tomographic angiography (CTA)
* Surgical or endovascular obliteration
* Able to obtain written informed consent from patient or surrogate
Exclusion Criteria:
* Pregnancy, as confirmed by routine urine test on admission
* Elevated liver function test at time of randomization, defined as more than three times the upper limit of normal
* On Statins, niacin, or fibrate therapy within 30 days of presentation
* Any vasospasm on the initial diagnostic angiogram
* Glasgow Coma Scale 5 or less at the time of randomization
* History of liver disease or active liver disease
* Hypersensitivity to statins
* Patient taking medication not recommended for concomitant use with Simvastatin (40 or 80 mg) as per the product label
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
85 Years
Study:
NCT00487461
Study Brief:
Protocol Section:
NCT00487461