Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 7:56 PM
Ignite Modification Date:
2025-12-24 @ 7:56 PM
NCT ID:
NCT06634004
Eligibility Criteria:
Inclusion Criteria:
Moyamoya
1. Clinical diagnosis of moyamoya disease as defined by gold-standard catheter angiography and consensus adjudication of imaging and neurological findings
2. Age = 18-60 years
3. Participants for the surgical revascularization aims must be scheduled for clinically indicated indirect surgical revascularization of at least one hemisphere
4. Speak and read English
Healthy controls
1. No major medical conditions
2. Age = 18-60 years
3. Speak and read English
4. Able to complete 2 study MRIs and all other study procedures
Exclusion Criteria:
-Both moyamoya and healthy controls
1. History of other major neurological conditions (including but not limited to Parkinson\'s disease, Alzheimer\'s disease, and Multiple Sclerosis) as confirmed by neuroimaging and neurological evaluation (central adjudication committee).
2. History of traumatic brain injury
3. Independent medical condition expected to lead to death within two years.
4. Condition associated with syndromic moyamoya (including but not limited to sickle cell disease, atherosclerosis, neurofibromatosis, Down syndrome).
5. Severe respiratory illness including but not limited to asthma or chronic obstructive pulmonary disease.
7\. Contraindication to 3 Tesla MRI 8. Pregnancy
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
69 Years
Study:
NCT06634004
Study Brief:
Protocol Section:
NCT06634004