Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:47 PM
Ignite Modification Date:
2025-12-24 @ 10:47 PM
NCT ID:
NCT00526669
Eligibility Criteria:
Inclusion Criteria:
* Has signed inform consent
* Untreated, newly diagnosed, advanced metastatic or unresectable gastric cancer, including the gastro-esophageal junction
* Tumor accessible to and patient consent for endoscopic biopsy at study start and after 7 days of single agent Lapatinib
* Measurable disease according to RECIST criteria
* Male or female \> or = 18 years of age
* Cardiac ejection fraction within the institutional range of normal as measured by echocardiogram
* must have adequate organ function as defined by baseline laboratory values
Exclusion Criteria:
* Gastric carcinoid, sarcomas, or squamous cell cancer
* Pregnant or lactating females
* Intractable nausea, vomiting, or gastro intestinal obstruction requiring decompression and drainage with a gastric tube or nasogastric suction.
* patients who require continuous enteral feeding
* Malabsorption syndrome or uncontrolled inflammatory GI disease (Crohn's or ulcerative colitis
* Known history of uncontrolled or symptomatic angina, arrhythmias, or congestive heart failure
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00526669
Study Brief:
Protocol Section:
NCT00526669