Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 1:32 PM
Ignite Modification Date:
2025-12-24 @ 1:32 PM
NCT ID:
NCT03291795
Eligibility Criteria:
Inclusion Criteria:
* Age 60 and above
* Able to speak English.
* seen, scheduled to be seen, or eligible to be seen in Preoperative Optimization of Senior Health (POSH) clinic prior to surgery
* scheduled for general, gynecologic or urologic surgery under the Enhanced Recovery After Surgery (ERAS) protocol, or eligible for ERAS protocol
* Lives within a \~1 hr drive of Duke
* Sedentary (not currently following physical activity guidelines)
* Ambulatory (assistive devices ok)
* Able to give informed consent
* Willing to perform prescribed exercises
Exclusion Criteria:
* Inmate of a correctional facility (i.e. prisoners).
* Documented or suspected family or personal history of malignant hyperthermia.
* Allergy or other contraindication to receiving isoflurane
* Receiving systemic chemotherapy after the first cognitive testing session and before the 6 wk follow up cognitive testing sessions.
* Major head trauma that occurs after the first cognitive testing session and before the 6 wk follow up cognitive testing sessions.
* Anginal symptoms, known coronary artery disease (CAD), or high cardiovascular risk per American College of Cardiology (ACC)/ American Heart Association (AHA) guidelines
* Taking anticoagulants that would preclude lumbar puncture per the American Society of Regional Anesthesia guidelines.
* Diagnosed history of dementia.
* Inability to ambulate independently.
* Otherwise not appropriate for study participation in the judgement of the Principal Investigator, such as (but not limited to) because the patient does not have the cardiopulmonary capacity to complete the exercise regimen.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
60 Years
Study:
NCT03291795
Study Brief:
Protocol Section:
NCT03291795