Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:04 PM
Ignite Modification Date:
2025-12-24 @ 11:04 PM
NCT ID:
NCT02524769
Eligibility Criteria:
Inclusion Criteria:
* Clinical diagnosis of Overactive bladder
* Clinical diagnosis of Postmenopausal:
* English language skills sufficient to complete questionnaires
* Clinical indication for vaginal estrogen use
* Not currently receiving vaginal estrogen therapy
Exclusion Criteria:
* Currently on systemic hormone replacement therapy (HRT) Have been on HRT within the past three months
* Clinical diagnosis of estrogen dependent malignancies
* Allergy to local estrogen therapy
* Insufficient language skills to complete study questionnaires
* Women with active, urinary tract infection
* Received antibiotics within the past two weeks
* Clinical diagnosis of stage 3 or 4 pelvic organ prolapse
* Patient unwilling to use vaginal estrogen preparation
* Currently on anticholinergic medication Have received anticholinergic medication within the past three months
* Previously failed two medications for treatment of OAB Previously received intra-vesicle botulinum toxin injections Previously had posterior tibial nerve stimulation Previously had implantation of sacral neuromodulator
* Patients wishing to start anticholinergic medication at the initial encounter
* Undiagnosed abnormal genital bleeding
* Clinical diagnosis of deep vein thrombosis (DVT) Clinical diagnosis of pulmonary embolism (PE)
* Clinical diagnosis of arterial thromboembolic disease
* Clinical diagnosis of liver dysfunction or disease
* Clinical diagnosis of protein C, protein S or antithrombin or deficiency other known thrombophilic disorders
Healthy Volunteers:
False
Sex:
FEMALE
Minimum Age:
55 Years
Study:
NCT02524769
Study Brief:
Protocol Section:
NCT02524769