Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-26 @ 10:37 AM
Ignite Modification Date:
2025-12-26 @ 10:37 AM
NCT ID:
NCT00564928
Eligibility Criteria:
Inclusion Criteria:
* Adenocarcinoma of the prostate
* Resolution of acute toxic side effects of prior chemotherapy
* Castration resistant disease despite ongoing chemical or surgical castration
* ECOG 0-1
* PSA greater than or equal to 2
* Group A -
* No Prior treatment for prostate cancer with cytotoxic chemotherapy (neoadjuvant, adjuvant treatment permitted if more than 2 years out)
* Group B
* Radiographic evidence of metastatic disease
* Prior tx with docetaxel-minimum of 2 cycles with progression by RECIST or PSA or intolerant of tx
* Maximum of 3 prior chemotherapies
Exclusion Criteria:
* Small cell carcinoma of the prostate
* Treatment within 2 weeks with approved, investigational, or small molecule
* Treatment within 4 weeks with biologic or external beam radiation
* ANC \<1,500 cells m3; Platelets \<100,000 mm3; Hemoglobin \<9.0g/dL
* AST/ALT \>2.5 ULN
* Serum creatinine \>3.0mg/dL
* Active keratitis or keratoconjunctivitis
* Previous treatment with 17-AAG, DMAG; or any other HSP-90 inhibitor
* Baseline Qtc \>450 mses
Healthy Volunteers:
False
Sex:
MALE
Minimum Age:
18 Years
Study:
NCT00564928
Study Brief:
Protocol Section:
NCT00564928