Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-26 @ 1:18 PM
Ignite Modification Date:
2025-12-26 @ 1:18 PM
NCT ID:
NCT02359006
Eligibility Criteria:
Inclusion Criteria:
* Males and females, between the ages of 18 and 55
* Diagnosed with opioid dependence and currently enrolled in methadone maintenance treatment
* Compliant in methadone maintenance treatment and on a stable dose for two weeks or greater
* No current dependence or abuse of any other drugs (other than tobacco or marijuana)
* No current medical problems
* For women:
* not pregnant as determined by pregnancy screening;
* not breast feeding; u
* using acceptable birth control methods;
* not experiencing moderate to severe premenstrual symptoms (may interfere with pain assessment);
* regular menstrual cycles
Exclusion Criteria:
* Current major psychiatric illnesses including mood, psychotic, or anxiety disorders
* History of major medical illnesses, including liver diseases, heart disease, or other medical conditions that the physician investigator deems contraindicated for inclusion in the study
* Current use of over-the-counter or prescription psychoactive drugs (including regular use of NSAIDS, antidepressant, anxiolytics, antipsychotics, mood stabilizers, psychostimulants) or drugs that would be expected to have major interactions with drugs to be tested, e.g., benzodiazepines, codeine, Percocet, and other opiate drugs
* Liver function tests (ALT or AST) greater than 3x normal
* Allergy to minocycline or other tetracyclines
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
55 Years
Study:
NCT02359006
Study Brief:
Protocol Section:
NCT02359006