Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:34 PM
Ignite Modification Date:
2025-12-24 @ 11:34 PM
NCT ID:
NCT00557856
Eligibility Criteria:
Inclusion Criteria:
* Advanced measurable or non-measurable solid tumors
* Adequate bone marrow function
* Adequate liver function
* Adequate renal function
* Be able and willing to comply with the study scheduled visits, treatment plans, laboratory tests and other procedures
Exclusion Criteria:
* Chemotherapy, radiotherapy, or any investigational cancer therapy within 4 weeks of first dose of study medication
* Active bleeding disorder, including gastrointestinal bleeding, as evidenced by hematemesis, hemoptysis or melena in the past 6 months
* Any of the following within the 12 months prior to starting study treatment: myocardial infarction, severe/unstable angina, coronary/peripheral artery bypass graft, congestive heart failure, cerebrovascular accident including transient ischemic attack, or pulmonary embolus; or any other active thromboembolic event
* QTc prolongation defined as QTc \>450 msec
* Patients with known brain metastasis
* Patients with peritoneal carcinosis at risk of bleeding
* Major surgical procedure within 4 weeks of treatment
* Pregnancy or breastfeeding
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00557856
Study Brief:
Protocol Section:
NCT00557856