Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-26 @ 5:19 PM
Ignite Modification Date:
2025-12-26 @ 5:19 PM
NCT ID:
NCT07261306
Eligibility Criteria:
Inclusion Criteria:
* Patients aged 18- 70 years of either gender.
* Only patients with Psoriasis Area and Severity Index (PASI) score of 10 or above, and/or Body Surface Area (BSA) involvement of 10% or more, will be included.
* Duration of plaque psoriasis for at least 6 months prior to the study.
* Psoriasis that has not shown adequate response to topical therapies
Exclusion Criteria:
* Individuals with other forms of psoriasis or other significant dermatological conditions that might interfere with the assessment of psoriasis.
* Participants currently receiving systemic corticosteroids, biologics, or any other immunosuppressive agents within 4 weeks prior to the start of the study will be excluded.
* Known hypersensitivity or contraindications to either methotrexate or tofacitinib.
* History of significant liver, kidney, hematologic/bleeding disorder, gastrointestinal/acid peptic disease, or immune system disorders.and any history of tuberculosis and malignancy.
* Pregnant or lactating women will not be eligible for the study.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
70 Years
Study:
NCT07261306
Study Brief:
Protocol Section:
NCT07261306