Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:40 PM
Ignite Modification Date:
2025-12-24 @ 11:40 PM
NCT ID:
NCT01687751
Eligibility Criteria:
Inclusion Criteria:
* Age greater or equal to 19 years of age
* Advanced cancer patient admitted to the Abbotsford Tertiary Palliative Care Unit
* Difficult to control or intractable symptom (REF 38, page 3)
* Midazolam CSCI would normally be considered for symptom management
* Informed consent is able to be provided in the English language
* Goals of care include do not resuscitate (DNR)
* For intractable symptoms, patient would prefer proportional sedation rather than no sedation or total sedation.
Exclusion Criteria:
* Second or third degree heart block (without pacemaker)
* Uncompensated congestive heart failure
* Heart rate less than 50 beats per minute
* Mean arterial blood pressure (MAP) \< 60
* Weight below 35 kg. or above 85 kg.
* Prior use within the preceding 14 days of high dose benzodiazepines equivalent to the use of 30 mg or more of midazolam or 6 mg or more of lorazepam per 24 hours.
* Currently enrolled in any other research study involving drugs or devices
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
19 Years
Study:
NCT01687751
Study Brief:
Protocol Section:
NCT01687751