Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:42 PM
Ignite Modification Date:
2025-12-24 @ 11:42 PM
NCT ID:
NCT04198051
Eligibility Criteria:
Inclusion Criteria:
1. Age 18-70 years old, male or female
2. Surgery specimens were clearly diagnosed as gastric cancer and colon cancer by histopathology
3. The operation method is not limited (both laparoscopic surgery and open surgery)
4. After the perioperative period, stop using antibiotics for not less than 2 weeks
5. It is planned to receive a chemotherapy regimen with a combination of platinum and fluorouracil for a period of 21 days (gastric cancer is the SOX or XELOX regimen, and colon cancer is the XELOX or FOLFOX regimen)
6. Blood routine, biochemical and other related laboratory tests showed no obvious abnormalities
7. There are no contraindications for related adjuvant chemotherapy indications.
Exclusion Criteria:
1. Neoadjuvant treatment before gastric and bowel cancer surgery
2. Previous history: He has suffered from intestinal microecology-related diseases such as cirrhosis, ulcerative colitis, Crohn's disease, irritable bowel syndrome, and urinary system diseases
3. Before the perioperative period, because of anastomotic fistula and gastrointestinal perforation, reoperation
4. The following drugs were used within 2 weeks before enrollment:
1. Various antibiotics, including antifungals (oral and intravenous)
2. Probiotic preparations, various prebiotic preparations, etc c Glucocorticoids; d Take drugs known to have a significant effect on the intestinal and urethral flora within half a year (such as proton pump inhibitors, purgatives, bismuth, adsorbents, non-steroidal anti-inflammatory drugs, etc.)
5. Other situations that the researcher considers unsuitable to participate in the experiment;
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
70 Years
Study:
NCT04198051
Study Brief:
Protocol Section:
NCT04198051