Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-26 @ 10:19 PM
Ignite Modification Date:
2025-12-26 @ 10:19 PM
NCT ID:
NCT07168512
Eligibility Criteria:
Inclusion Criteria:
* Age 20-55 years.
* Clinical diagnosis of cervicogenic headache according to International Classification of Headache Disorders (ICHD-3) criteria (headache attributed to cervical disorder).
Exclusion Criteria:
* History of major cervical spine pathology such as fracture, dislocation, congenital malformation, tumor, infection, or inflammatory arthritis (e.g., rheumatoid arthritis, ankylosing spondylitis).
* Previous cervical spine surgery or fusion at any level.
* Red flag symptoms indicating serious pathology (e.g., progressive neurological deficit, unexplained weight loss, fever, history of cancer).
* Systemic or neurological disorders that may affect neck function or headache (e.g., multiple sclerosis, Parkinson's disease).
* Severe osteoporosis or metabolic bone disease that contraindicates cervical X-ray imaging.
* Vascular disorders such as vertebrobasilar insufficiency or carotid artery disease.
* Pregnancy or breastfeeding (due to radiation exposure during cervical radiography).
* Unstable psychiatric conditions (e.g., severe depression, psychosis) that may interfere with participation or adherence.
* Recent physiotherapy or manual therapy targeting the cervical region within the past 6 weeks, or planned during the study outside the protocol.
* Use of botulinum toxin or steroid injections to the neck or head region in the past 6 months.
* Contraindications to manual therapy or exercise (e.g., acute cervical disc herniation, severe myelopathy, unstable cardiovascular disease).
* Inability to understand study procedures, comply with treatment sessions, or provide informed consent.
* Symptoms of migraine, tension-type headache (TTH), or any other headache apart from cervicogenic headache.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
20 Years
Maximum Age:
55 Years
Study:
NCT07168512
Study Brief:
Protocol Section:
NCT07168512