Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:51 PM
Ignite Modification Date:
2025-12-24 @ 11:51 PM
NCT ID:
NCT04123951
Eligibility Criteria:
Inclusion Criteria:
* Age great than 18 years old
* Prevalent RTR longer than 1year
* Able and willing to give informed consent
* Increased cardiometabolic risk, with at least one of:
Diabetes mellitus Dyslipidaemia Hypertension History of ischaemic heart disease or cerebrovascular disease Obesity (BMI above 30)
Exclusion Criteria:
* Unable to undertake exercise due to physical or psychological barriers
* Unable to undergo CMR scanning (incompatible implants, claustrophobia, allergy to agents)
* Contraindication to exercise training (American College of Sports Medicine guidelines)
* Female participants who are pregnant, lactating, or planning pregnancy during the course of the study.
* Scheduled elective surgery or other procedures requiring general anaesthesia during the study.
* Any other significant disease or disorder (i.e. significant co-morbidity including unstable hypertension, potentially lethal arrhythmia, myocardial infarction within 6 months, unstable angina, active liver disease, uncontrolled diabetes mellitus (HbA1c greater than or equal to 9%), advanced cerebral or peripheral vascular disease) which, in the opinion of the patient's own clinician the Principle Investigator may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant's ability to participate in the study.
* Inability to give informed consent or comply with testing and training protocol for any reason.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04123951
Study Brief:
Protocol Section:
NCT04123951