Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:14 AM
Ignite Modification Date:
2025-12-25 @ 12:14 AM
NCT ID:
NCT01044758
Eligibility Criteria:
Inclusion Criteria:
* All: English as a first language; right handed; able to complete written informed consent.
* MCI subjects: In addition to above, must meet criteria for amnestic Mild Cognitive Impairment (MCI). This includes a memory complaint corroborated by an informant; impaired memory function for age and educational level; preserved general cognitive function; intact abilities of daily living; no clinical dementia.
* Age matched Controls: Must have memory and cognitive status that is normal for their age.
Exclusion Criteria:
* Familial Alzheimer's Disease (AD) due to known genetic mutations
* AD with Parkinsonian features; major psychiatric or behavioral disorders (e.g. depression, agitation, psychosis, manic-depressive disorder)
* Primary or metastatic intracranial neoplasm
* History of severe head trauma
* Intra-cerebral hemorrhage
* Seizure disorder
* Hemispheric stroke
* Presence of a progressive central nervous system disease
* Presence of lacunar infarcts
* Medical contraindications to MRI including cardiac pacemaker, presence of intraocular or intracranial metallic objects
* Any known allergy to levetiracetam or behavioral problems that are a contraindication to taking Levetiracetam (e.g. agitation)
* Prescribed use of anti-seizure medications.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
50 Years
Maximum Age:
85 Years
Study:
NCT01044758
Study Brief:
Protocol Section:
NCT01044758