Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:40 AM
Ignite Modification Date:
2025-12-25 @ 12:40 AM
NCT ID:
NCT04607967
Eligibility Criteria:
Inclusion Criteria:
* Patients over 18 years of age
* Admitted to the Emergency Department for acute respiratory distress :
* Respiratory rate ≥ at 25 cycles/min.
* And SpO2 ≤ at 95% without or with oxygen whatever the mode.
* And clinical signs of respiratory distress (pulling, thoraco-abdominal swinging).
* And PaO2/FIO2 ratio \< 300mmHg.
Exclusion Criteria:
* Hypercapnic patients (PaCO2 \> 45mmHg) with respiratory acidosis (pH\<7.30).
* Indication for non-invasive ventilation or early invasive mechanical ventilation according to current scientific recommendations (acute pulmonary edema, Chronic obstructive pulmonary disease decompensation, or others).
* Dyspnea of traumatic origin.
* Traumatic pneumothorax.
* Hemodynamic instability (PAM\<65mmHg).
* Patients treated with Mobile Emergency and Resuscitation Service (SMUR) who have already received cardiac or pulmonary treatment.
* Patients with cognitive deterioration (Glasgow score less than 13, dementia or mental failure that would prevent good cooperation).
* Patients with lesion(s) of the oro-nasal sphere contraindicated for the implementation of High Flow Nasal Oxygen Therapy.
* Subject unlikely to cooperate in the study and/or low cooperation anticipated by the investigator.
* Subject without health insurance.
* Pregnant woman.
* Subject being in the exclusion period of another study or included in the "national volunteer file".
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04607967
Study Brief:
Protocol Section:
NCT04607967