Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 2:06 PM
Ignite Modification Date:
2025-12-24 @ 2:06 PM
NCT ID:
NCT00634595
Eligibility Criteria:
Inclusion Criteria:
* histologically or cytologically confirmed recurrent or metastatic head and neck squamous carcinoma or nasopharyngeal carcinoma
* the tumor was amenable to direct injection and measurement ( \> 2 cm)
* an Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2
* a life expectancy over three months
* the absence of serious medical or psychiatric disorders
* serum creatinine \< 1.5 mg/dL; WBC count \>3,000/mm3, platelet count \> 80,000/mm3, hemoglobin \> 8 g/dL; total bilirubin value \< 1.5 times the upper limit of normal \[ULN\], ALT level \< 2.5 times ULN, AST \< 2.5 times ULN.
Exclusion Criteria:
* pregnant or breast feeding
* a history of brain metastases or a primary brain tumor
* a history of hemorrhagic diathesis
* a history of corticosteroids or immunosuppressives use within four weeks of study entry
* a history of immune deficiency disorder or organ transplant
* has evidence of active adenovirus infection or uncontrolled infection
* received any chemotherapy or radiotherapy within four weeks of study entry
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT00634595
Study Brief:
Protocol Section:
NCT00634595